Welcome to ITLS

We undertake the complete responsibility of ensuring the success of your project by efficiently coordinating and overseeing all aspects, starting from initial negotiations to project conclusion. Our team brings valuable expertise and an extensive network of carefully selected experts, toxicologists, and more than 20 accredited testing laboratories and service providers, each with a remarkable track record spanning over two decades in the industry.

Our Services

At ITLS in vitro - Testing Laboratory Services we provide an extensive database comprising a wide range of in vitro tests and services for the registration and research & development of chemicals, pharmaceutical substances, cosmetics, biocides, pesticides, medical devices, and veterinary medicinal products. Our tests are conducted in accredited laboratories, adhering to the principles of good laboratory practice (GLP). This ensures reliable and high-quality results for your regulatory and scientific needs.

Streamline your in vitro testing registration process with our expert assistance. We provide comprehensive support and guidance to ensure a smooth and successful registration of your in vitro testing methods, adhering to regulatory requirements. Trust us to navigate the complexities and help you gain the necessary approvals for your innovative in vitro testing approaches.

in vitro - Testing
for Registration

Worldwide: > 20 GLP - accredited in vitro - testing laboratories, thus large available test capacities and fast project placement and test execution
All required OECD – laboratory in vitro -tests for registration
in vitro - Toxicology, Mutagenicity, Genotoxicity, Endocrine Disruption, Skin- and Eye Irritation / Corrosion, in vitro - Skin Sensitisation, Phototoxicity, Cytotoxicity Assays
Excellent project management and study monitoring
Proficient regulatory and toxicological expertise
Optimal test strategy development

Efficient project management is key to successful toxicology studies. Our experienced team of project managers will ensure seamless coordination, timely execution, and meticulous oversight, guiding you through every stage of your toxicology study to deliver reliable and high-quality results. Trust us to handle the complexities and optimize your toxicology projects for successful outcomes.

Project Management and Study Monitoring

Accelerated test execution facilitated by our comprehensive project management and study monitoring
Minimized workload as we assume full responsibility
Stay informed with our regular project status reports (provided every 2-4 weeks)
Customer-centric and customized project management approach: You have the autonomy to choose the level of support and task delegation that aligns with your preferences.

Accelerate your Research & Development initiatives with our advanced in vitro testing services. Our state-of-the-art laboratory facilities and expert team provide efficient and reliable testing solutions, delivering valuable data and insights to drive innovation and expedite the development of safe and effective products. Experience the power of in vitro testing for R&D and gain a competitive edge in your industry.

in vitro - Testing
for Research & Developement

Newest in vitro - Testing innovations
Large in vitro - laboratory network with the latest in vitro techniques
in vitro - concepts and test strategies for efficient research and product development
in vitro - Laboratory Testing under GLP or non-GLP
Product and substance screenings
Safety assessment
Risk assessment
Competent toxicological expertise

Ensure a comprehensive and successful registration process by utilizing our additional services to complete your registration dossier. Our expert team will guide you through the entire process, offering support in compiling the necessary documentation, data analysis, and ensuring compliance with regulatory requirements. Trust us to streamline your registration journey and maximize your chances of a seamless dossier submission.

Other Services
to complete the Registration Dossier

We have a large network of trustworthy cooperation laboratories and partners to carry out all required OECD - studies to complete the registration dossier
Physico- and chemical properties, ecotoxicology, analytical chemistry, biodegradation, environmental fate etc.
REACH testing services
Biocide testing and evaluation
Cosmetics safety assessment and testing
Preclinical laboratory testing for pharmaceutical compounds
Creating and updating material safety data sheets

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Quick Project Initiation: personal - competent - reliable

We excel at executing projects with speed and efficiency, providing a personal touch coupled with high competence and reliability. Our services include immediate regulatory consulting, leveraging the expertise of our in-house toxicologists, and offering optimal test strategy development. You can count on our team to deliver prompt and effective solutions tailored to your specific needs.

OECD - in vitro - Studies offered by ITLS

OECD Test No. 471 Bacterial Reverse Mutation Test

OECD Test No. 428

Skin Absorption: in vitro Method

OECD Test No. 437

Bovine Corneal Opacity and Permeability Test Method

OECD Test No. 432

In Vitro 3T3 NRU Phototoxicity Test

OECD Test No. 455

In Vitro Assays to Detect Estrogen Receptor Agonists and Antagonists

OECD Test No. 473 In Vitro Mammalian Chromosomal Aberration Test

OECD Test No. 431

in vitro skin corrosion: reconstructed human epidermis (RHE) test method

OECD Test No. 467

Defined Approaches for Serious Eye Damage and Eye Irritation

OECD Test No. 498

In vitro Phototoxicity - Reconstructed Human Epidermis Phototoxicity test method

OECD Test No. 456

H295R Steroidogenesis Assay

OECD Test No. 474 Mammalian Erythrocyte Micronucleus Test

OECD Test No. 435

In Vitro Membrane Barrier Test Method for Skin Corrosion

OECD Test No. 491

Short Time Exposure In Vitro Test Method

OECD Test No. 457

Yeast estrogen screen

OECD Test No. 458

Androgen receptor transactivation

OECD Test No. 475 Mammalian bone marrow chromosome aberration test

OECD Test No. 439

in vitro Skin Irritation: Reconstructed Human Epidermis Test Method

OECD Test No. 492

(RhCE) test method for identifying chemicals not requiring classification and labelling for eye irritation or serious eye damage

OECD Test No. 493

Estrogen or androgen receptor binding affinity (US EPA TG OPPTS 890.1150)

OECD Test No. 492B

Reconstructed Human Cornea-like Epithelium (RHCE) Test Method for Eye Hazard Identification

OECD Test No. 476 In Vitro Mammalian Cell Gene Mutation Tests using the Hprt and xprt genes

OECD Test No. 442A

Skin Sensitization

OECD Test No. 442B

Skin Sensitization (LLNA: BrdU ELISA)

OECD Test No. 442C

In Chemico Skin Sensitisation

OECD Test No. 442D

In Vitro Skin Sensitisation

OECD Test No. 483 Mammalian Spermatogonial Chromosomal Aberration Test

OECD Test No. 442E

In Vitro Skin Sensitisation

OECD Test No. 487

in vitro Mammalian Cell Micronucleus Test

OECD Test No. 490

in vitro Mammalian Cell Gene Mutation Tests Using the Thymidine Kinase Gene

OECD Test No. 496

In vitro Macromolecular Test Method for Identifying Chemicals Inducing Serious Eye Damage and Chemicals Not Requiring Classification for Eye Irritation or Serious Eye Damage

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